"Taking into account other types of cancer — including lung, breast, pancreatic, prostate and melanoma — a total of 23 clinical trials are currently registered at clinicaltrials.gov that are investigating the ketogenic diet as an adjunct to standard cancer therapy. Over the last decade, research investigating the ketogenic’s diet role in basic cancer research and in emerging therapies has burgeoned, with more than 170 studies or theoretical papers currently in the research literature. The number is increasing each month."
Why is there so much research on ketogenic diets for cancer, not so much on high carbohydrate diets (grain-based, macrobiotic, vegan, etc.)? Simply because it is a fact that cancer cells are glucose-dependent whereas healthy cells are not, so restricting glucose will harm cancer cells but not healthy cells.
The only way to get a metabolic effect similar to a ketogenic diet while eating a high carbohydrate diet like the usual grain-based macrobiotic or vegan diet is to severely restrict food (calorie) intake so that you rapidly lose body mass, forcing your body to get most of its energy from animal fat, i.e. the fat on your own body. I think this explains why most if not all reports of some success in controlling cancer with plant based diets (whether macrobiotic, raw, vegan, etc.) indicate that the subject has a dramatic loss of body weight during the "healing" phase.
The problem with a carbohydrate based diet for cancer management is that you can't starve yourself forever. At some point you have to start eating a sufficient number of calories to maintain health and function of non-cancerous tissues. If you do this with a glucose-rich diet such as the grain-based macrobiotic diet, you will recreate the conditions that favor the glucose-hungry cancer cells.
I hypothesize that this is why cancer has emerged in and even taken the lives of several prominent promoters of the grain-based macrobiotic diet, including among the Kushi family.
Michio Kushi, promoter of the grain-based macrobiotic diet, and author of The Cancer Prevention Diet, which advocated a grain-based diet for prevention of cancer, died at 88 years from pancreatic cancer after a bout with colon cancer.
Michio's wife Aveline and daughter Lily both died after developing cervical cancer. As discussed in the linked article, cervical cancer is primarily linked to HPV, which according to conventional medicine is strongly linked to sexual promiscuity and transmission.
Apparently cancer has also claimed the lives of several women who were highly faithful to a vegan macrobiotic diet and long-term teachers of macrobiotic cooking classes at the Kushi Institute.
The underlying hypothesis that animal fat and protein cause and promote cancer lacks a strong scientific basis. If it were so, fasting, which is running on your own body fat and protein, which are ANIMAL fat and protein, would promote cancer, when in fact it is well established that short-term fasting (i.e. running your body exclusively on mammalian fat and protein) strongly undermines cancer cells but preserves healthy cells.